Rett Syndrome Prevention

Presently, Rett syndrome cannot be prevented. In most cases, the genetic mutation that is responsible for the disorder occurs randomly and spontaneously. However, couples who already have a child with Rett syndrome or have another family member who is affected may choose to discuss genetic testing with their doctor. In a family who has had a child with Rett syndrome, the probability of having another child with Rett syndrome is very low but mothers should undergo carrier testing since recurrence risk is 50% if the mother is found to be a carrier.